Male birth control pill shows promise in early human trials

A medical researcher. (photo via

The once-daily oral pill, called dimethandrolone undecanoate or DMAU, is made up of two steroid hormones — testosterone and progestin — that are chemically modified to suppress sperm production. Over the course of a month, it showed positive results, with little to no adverse side effects.

The study was led by researchers Dr. Stephanie Page of the University of Washington and Dr. Christina Wang of the University of California, Los Angeles. Its findings were presented Sunday at the Endocrine Society’s 100th annual meeting in Chicago.

The study evaluated 100 heathy men between 18 and 50 years old. They were assigned to groups with at least three different doses of DMAU, and some received a placebo.

It was the first time researchers evaluated repeated doses of DMAU to make sure it’s safe and to identify proper dosage in future studies. The group that received the highest dose, 400 milligrams, had the greatest suppression of sperm production and tolerated the medication well.


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